Zocef tab Adult & adolescent ≥13 yr Pharyngitis/tonsillitis 250 mg bid for 10 days.
Acute bacterial maxillary sinusitis 250 mg bid for 10 days.
Acute bacterial exacerbations of chronic bronchitis 250 or 500 mg bid for 10 days.
Secondary bacterial infections of acute bronchitis 250 or 500 mg bid for 5-10 days.
Uncomplicated skin & skin structure infections 250 mg bid for 7-10 days.
Uncomplicated gonorrhea 1,000 mg as a single dose.
Early Lyme disease 500 mg bid for 20 days.
Ped patient who can swallow tab whole Acute otitis media 250 mg bid for 10 days.
Acute bacterial maxillary sinusitis 250 mg bid for 10 days.
Zocef susp Adult Uncomplicated UTI 250 mg bid.
Resp tract infections 250-500 mg bid.
Childn >3 mth 250 mg bid or 10 mg/kg bid. Max: 250 mg daily.
Childn >2 yr Otitis media 250 mg bid or 15 mg/kg bid. Max: 500 mg daily.
Zocef Hospi Adult & childn ≥40 kg Community acquired pneumonia & acute exacerbations of chronic bronchitis, soft tissue infections eg, cellulitis, erysipelas & wound infections, intra-abdominal infections 750 mg every 8 hr as IV or IM.
Complicated UTI including pyelonephritis 1.5 g every 8 hr as IV or IM.
Severe infections 750 mg every 6 hr as IV or 1.5 g every 8 hr as IM.
Surgical prophylaxis for GI, gynecological surgery including caesarean section) & orthopaedic operations 1.5 g upon induction of anesth. May be supplemented w/ two 750 mg after 8 & 16 hr as IM.
Surgical prophylaxis for CV & oesophageal operations 1.5 g upon induction of anesth followed by 750 mg every 8 hr for a further 24 hr as IM.
Infant & toddler >3 wk & childn <40 kg Community acquired pneumonia, complicated UTI including pyelonephritis, soft-tissue infections eg, cellulitis, erysipelas & wound infections, intra-abdominal infections 30-100 mg/kg/day as IV in 3 or 4 divided doses. A dose of 60 mg/kg/day is appropriate for most infections.
Infant from birth to 3 wk Community acquired pneumonia, complicated UTI including pyelonephritis, soft-tissue infections eg, cellulitis, erysipelas & wound infections, intra-abdominal infections 30-100 mg/kg/day in 2 or 3 divided doses as IV.
Renal impairment CrCl 10-20 mL/min/1.73 m2 750 mg bid,
<10 mL/min/1.73 m2 750 mg once daily.
Patient on haemodialysis 750 mg dose should be given IV or IM at the end of each dialysis.
Patient in renal failure on continuous arteriovenous haemodialysis (CAVH) or high-flux haemofiltration in intensive therapy units 750 mg bid.
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